NSC 330 CAD & HF Agents 100% Correct Review Solution A+ Graded 2024 Nitrate Uses - ANS-1st line treatment for immediate and long term treatment/prevention of angina Nitrate AEs - ANS-1. Headache (most common) take with acetaminophen 2. Hypotension Orthostatic 3. Reflex tachycardia 4. Flushed feeling 5. Dizziness, syncope Nitrates Sublingual/Spray - ANS-*Acute*: onset 1-3 mins Lie or sit prior to taking to reduce fall risk from drop in BP 0.4mg q 5mins, 3 dose max *Exertional*(prevention): o.4mg 5-10mins prior to activity Duration of 30-60mins Storage- protect from light, heat and moisture Always have available! Expiration 6 months Nitrates long acting/maintenance - ANS-Not for acute angina isosorbide mononitrate (Imdur) PO daily to prevent angina Transdermal Patches (Nitro-Dur) apply to hair free upper body; remove at HS for 8hrs Nitroglycerin paste- may be used for angina prevention or elevated BP; remove at night IV nitroglycerin - ANS-1. Must use pump! 2. Mix with NS or D5W3. Glass bottle with special tubing- protect from light and vented tubing 4. Titrate q 5mins according to pain/angina; need to get to 0; Check BP to ensure not too low and HR to ensure not to high Nitrates Nursing Implications - ANS-Monitor BP before, during,