Pathoph ysiology - 50 MC Qs with Ans wers1. Which of the following is the primary defect in T ype 1 Diabetes Mellitus?A. Insulin resistanceB. Increased insulin secretionC. Autoimmune destruction of beta cellsD. Increased glucagon secretionAnswer: C. Autoimmune destruction of beta cells2. Which disease is characterized by destruction of myelin in the central nervous system?A. Parkinson s diseaseB. Multiple sclerosisC. Myasthenia gravisD. Alzheimer s diseaseAnswer: B. Multiple sclerosis3. Which of the following is a hallmark feature of Parkinson s disease?A. SpasticityB. Tremor at restC. SeizuresD. HyperreflexiaAnswer: B. T remor at rest4. Atherosclerosis primarily affects which structure?A. V einsB. ArteriesC. CapillariesD. L ymphatic vesselsAnswer: B. Arteries5. Which electrolyte imbalance is commonly associated with chronic kidney disease?A. HypokalemiaB. HyperkalemiaC. HypernatremiaD. HypocalcemiaAnswer: B. Hyperkalemia6. Which condition is characterized by destruction of alveoli leading to enlarged air spaces?A. AsthmaB. EmphysemaC. PneumoniaD. T uberculosisAnswer: B. Emphysema7. Which of the following is the primary cause of myocardial infarction?A. Coronary artery spasmB. Coronary artery thrombosisC. Aortic stenosisD. PericarditisAnswer: B. Coronary artery thrombosis8. The deficiency of dopamine in the brain is associated with:A. Parkinson s diseaseB. Alzheimer s diseaseC. EpilepsyD. Multiple sclerosisAnswer: A. Parkinson s disease9. Which of the following conditions is characterized by chronic airway inflammation and