Ons Oncc Chemo Renewal Exam 2024 With 100% Correct Answers

Consider the potential toxicity related to each drug. Understand the monitoring guidelines for each drug. Have knowledge of clinically significant signs and symptoms. {Ans: Key Points for Combination Therapy}Cold sensory neuropathy {Ans: Which of the following is a unique side effect that occurs with the agent oxaliplatin?}Totect Apply ice pack (remove 15 minutes prior to Totect treatment). Infusion should be initiated within six hours of extravasation. Infused over 1-2 hours for three days in an area other than the extravasation site The dose recommended is based on the patients' body surface area. • Day 1: 1,000 mg/m2 • Day 2: 1,000 mg/m2 • Day 3: 500 mg/m {Ans: Extravasation Tx: Anthracyclines --- Daunorubicin, doxorubicin, epirubicin, idarubicin}Per the NCCN guidelines (http://www.nccn.org/professionals/physician_gls/pdf/antiemesis.pdf) on Antiemesis, the most likely classes of agents that would be used as premedication for a moderately emetic risk regimen include: Steroids usually dexamethasone, 5HT3 antagonists like palonosetron or ondansetron, with or without neurokinin 1 antagonists like aprepitant or fosaprepitant. Prokinetic agents like metoclopramide are sometimes used PRN for low risk regimens and breakthrough CINV. Other classes of agents like proton pump inhibitors, H2 blockers, and benzodiazepines are utilized for CINV prevention and control as well and