Ons Chemotherapy Biotherapy Certification Exam 2023 With Correct Answers

5 fluorouracil (5 FU) {Ans: -IV oral topic and opthalmic formalation -can cause hyperpigmentation, increased mucositis, photosensitivity, diarrhea -capcytobine is the oral form - needs to be taken 2x day, hand foot syndrome can occur -INR monitoring}cyclophasmide {Ans: hair loss 10-14 days post treatment -can be given peripherally -hemmorhagic cystitis - hydration is key, high dose may need bladder protection -easier to give than iphosphamide}Administration considerations {Ans: routes: oral- convenient, decreased time in hospital, expensive, and difficulty with adherence, inconsistent adborption- food drug interactions nursing: verify dose, PPE, no crushing (pharmacist must do so if NG) SQ: ease, well tolerated, inconsistent absorption, increased fat could increase risk of misplacement. pain/ bleed/ bruising IM: rapid absorption, can cause nerve damage, tissue necrosis, PPE, insert at 90 deg angle, avoid massage intraperitoneal: catheter or IP port. directly into peritoneal cav, infection risk, abdominal pressure, bleeding, diarrhea, per, infection, anaphylaxis intrathecal: CNS malignancies,methotrexate and cytarabine - surgical procedure, lumbar puncture is invasive intrapleural intravesicular: bladder cancer intra aterial IV - continuous or push (through fre flowing IV, attach at injection port, aspirate for blood, slowly admin at a rate of 1-2ml/min -vesicant chemo admin: remain with patient through entire infusion