Target levels for immunosuppressants are based on a number of factors including: {Ans: Indication for tx, use of induction therapy, kidney function, overall condition of pt.}Side effects of corticosteroids {Ans: DM, HTN, high cholesterol, weight gain, fluid retention, indigestion, bone loss(long term use),}Side effects of calcineurin inhibitors(tacrolimus and cyclosporine) {Ans: Tremors, headaches, HTN, nephrotoxicity, high glucose levels, hair growth or loss, increased risk of cancer}Mycophenolate mofetil (CellCept) side effects {Ans: Low white cells(especially neutrophils), diarrhea(splitting dose may help), vomiting, headaches, HTN}What to monitor post liver bx {Ans: VS, signs of bleeding(tachycardia, hypotension) If has T tube monitor for blood in bile Hgb hct typically check 4 hrs after bx Bed rest 4-6 hrs after bx}Azathioprine(imuran) side effects {Ans: Leukopenia, joint pain, n&v, dizziness, stomach upset}What can cause a post liver transplant patient whose initial postop neurological course is normal to develop sudden deterioration in neurological status? {Ans: Intracranial bleed}Lab changes are indicate of graft dysfunction. Which values will be elevated for liver tx? {Ans: Elevated AST and ALT}Antiproliferative agents {Ans: Azathioprine (imuran) Mycophenolate mofetil(cellcept) Mycophenolic Acid(myfortic)}De Novo seizures can occur post liver transplant and can be caused by what? {Ans: