Cctc Certification Review Questions & Answers Rated 100% Correct!!

Risk of primary non-function after liver transplant is: {Ans: 4-6%}What is NASH? {Ans: Non-alcoholic steatohepatitis. Can lead to cirrhosis 3rd common indication for liver TX.}Sirolimus(rapamycin/rapamune) side effects {Ans: Leukopenia, thrombocytopenia, anemia, HTN, rash, acne, diarrhea, poor wound healing *dyslipidemia is a long term complication*}What can lead to hypoxic ischemic encephalopathy post liver transplant? {Ans: Significant peri-operative hypotension}Antiproliferative agents {Ans: Azathioprine (imuran) Mycophenolate mofetil(cellcept) Mycophenolic Acid(myfortic)}Side effects of calcineurin inhibitors(tacrolimus and cyclosporine) {Ans: Tremors, headaches, HTN, nephrotoxicity, high glucose levels, hair growth or loss, increased risk of cancer}What color should t tube drainage be post liver Tx? {Ans: Golden brown}Signs of acute rejection s/p liver Tx {Ans: Fever, listlessness, liver pain, loss of appetite, irritability, fatigue, abdominal distention, jaundice, abnormal transaminases}Factors related to primary nonfunction of new liver include: {Ans: Donor age, prolonged cold ischemic time, prolonged donor hospital stay with periods of hypotension, preservation injury during donor surgery, and donor steatosis(fat in liver)}What are causes of cholestasis post liver transplant {Ans: Rejection Sepsis Drug toxicity Preservation injury}Early Indicators of non functioning liver: {Ans: decrease in bile production extreme edema of organ Abnormal color of organ upon reperfusion(mottled, gray, pale)