Histopathology - Study Guide - Medical Laboratory Science

RETROGRESSIVE CHANGES OF CELLS - organs or tissues smaller than normal Aplasia - incomplete development of a tissue or an organ Agenesia - complete non-appearance of an organ Hypoplasia - failure of an organ to reach its full maturity Atresia - failure of an organ to form an opening Atrophy -reduction in size of cells, tissue, or organs PROGRESSIVE CHANGES - organs or tissues larger than normal Hypertrophy - is increased organ size resulting from an increase in the size of constituent cells, without an increase in the cell number Hyperplasia - increase in number of cells due to growth of new cells DEGENERATIVE CHANGES - abnormal cellular growth patterns Metaplasia -reversible phenomenon which involves transformation of one adult cell type to another Dysplasia -reversible change which involves alteration of adult cells through variation in size, shape and orientation Anaplasia (dedifferentiation) - a marked regressive change in adult cells towards more primitive cell types Neoplasia - continuous abnormal proliferation of cells under no control without any purpose or function Types of Necrosis 1. Coagulative necrosis - characterized by the formation of a gelatinous (gel-like) substance in dead tissues in which the architecture of the tissue is maintained, and can be