Determine The Effect Of A Dietary Intervention

www.medscape.com Abstract and IntroductionAbstractObjectives To determine the effect of a dietary intervention and micronutrient supplementation on self-reported infections inolder adults.Design A randomized, placebo-controlled intervention trial.Setting Community living older people in South Yorkshire, United Kingdom.Participants Two-hundred seventeen older adults aged 65 to 85.Intervention Participants were randomized to a dietary intervention, a daily micronutrient supplement, or placebo for 3months, with a 3-month follow-up.Measurements Self-reported measures of infection were reported over the 6-month study period. Secondary outcomemeasures were nutritional status, dietary intake, quality of life, and depression.Results Self-reported measures of infection over the 6-month duration of the study were significantly different between thetreatment groups. The number of weeks in which illness affected life and the number of general practitioner and hospitalvisits were significantly lower in the food and micronutrient groups than in the placebo group. The number of weeks in whichsymptoms of an infection were described was significantly lower in the food group than the placebo and micronutrientgroups. Significant improvements in biomarkers of micronutrient status were achieved in the food and micronutrient groupsand showed significantly greater change than observed in the placebo group. Significant improvement in dietary intakes wasobserved in the food group only.Conclusion Improving dietary intake and micronutrient status reduces the clinical