Pharmacokinetics And Pharmacodynamics In Clinical Practice: Me

PHARMACOKINETICS AND PHARMACODYNAMICS IN CLINICAL PRACTICE: MEDICATION ABSORPTION, DISTRIBUTION, METABOLISM, EXCRETION, DRUG INTERACTIONS, AND INDIVIDUALIZED DOSING FOR SAFE PATIENT OUTCOMES A nurse is providing teaching with a client, who has schizophrenia, about strategies to minimize the anticholinergic effects of fluphenazine. Which of the following instructions should the nurse suggest for the client? Chew sugarless gum to moisten the mouth. When taking action, the nurse should instruct the client who is taking fluphenazine and is experiencing anticholinergic effects to chew sugarless gum. This instruction would provide moisture to the client's mouth and decrease the severity of dry mouth which is an anticholinergic adverse effect. Gentamicin Gentamicin is a narrow-spectrum aminoglycoside antibiotic prescribed to treat serious infections caused by aerobic bacilli Complications of Gentamicin Gentamicin can injure cells of the proximal renal tubules. Naproxen and other NSAIDs can cause renal insufficiency. The glomerular filtration rate of the kidneys decreases with advanced age, making this client at increased risk for nephrotoxicity. What lab values should a nurse monitor for a patient taking Gentamicin? BUN Blood creatininePeak and trough levels of gentamicin Specific gravity of urine Urinalysis BUN blood urea nitrogen Nursing actions for a client taking gentamicin Monitor intake and output. Notify the