Module 3: Pharmacokinetics And Pharmacodynamics Study Guide Questions And Correct Answers

Passive diffusion of drugs into the glomerulus for elimination. Small, non-ionic and non-protein bound passes through. {Ans: Glomerular Filtration}The percent of drug administered that actually reaches systemic circulation. Best is 100. Blood supply, absorptive surface area, mechanism of absorption and dosage effect this. {Ans: Bioavailability}A microsomal detoxifying enzyme in the liver that has a role in metabolism. {Ans: Cytochrome P450}What drugs pass through the cell membrane easiest? {Ans: lipophilic drugs which are usually non iodized}cytochrome P450 {Ans: The general name for a large class of enzymes that play a significant role in drug metabolism and drug interactions.}The movement of molecules from an area of high concentration to an area of low concentration. No energy required. {Ans: Passive Diffusion}