Gms 6551 Drug Studies Exam Questions (68 Terms) With Verified Definitions Updated 2024

Translational research {Ans: - bench to bedside - bedside to community - encompasses "Bidirectional continuum" - T0-T4}Pharmacokinetics {Ans: - dose given & how often - absorption - distribution - metabolism - excretion - determined in vitro or in vivo}Pharmacokinetic considerations {Ans: - PK ADME - absorption - distribution - metabolism - excretion}Data collected in Phase I {Ans: - Pharmacokinetics (ADME + half life) - Pharmacodynamics}Specificity {Ans: - probability that an individual without the disease tests negative - more important in diagnostics (right side of graph)}SAR {Ans: - structure activity relationships - optimize lead compounds - makes drug better - elimation of unneeded effects}