cluster headaches {Ans: Unilateral, usually behind or around the eye or temple Deep, continuous, severe Abrupt onset; peaks with in minutes Duration up to 2 hours Lacrimation, rhinorrhea, miosis, ptosis, eye edema, infection Worsens sensitivity to alcohol during attack}Systemic fungal infections, live virus vaccines, caution in pediatric/pregnant/breastfeeding patients {Ans: Contraindications for glucocorticoids}gram - {Ans: third generation cephalosporins can penetrate spinal fluid & cover gram ___ anaerobes}rebound headaches {Ans: side effect of abortive headache medication}Methotrexate {Ans: RA agent that can damage liver, bone marrow and lungs}neonates {Ans: especially sensitive to drugs that are eliminated primarily by the hepatic metabolism}