Nu578 - Unit 1 Test With Correct Answers

Treatment of anticholinergic (antimuscarinic) poisoning {Ans: physostigmine *activated charcoal also used to decrease intestinal absorption}Adverse effects of Alpha 2 blockers {Ans: reflex tachycardia}Pilocarpine (Pilocar, OcusertPilo) {Ans: muscarinic agonist used for Glaucoma; oral Tx for Sjogren's}Albumin {Ans: Binds acidic drugs}Protein (albumin) binding {Ans: Prevents bound drug molecules from leaving the bloodstream Prolongs the distribution phase (Increases half-life)}Barriers to distribution {Ans: - Blood brain barrier - Placenta}