risk factors for hypernatremia {Ans: elderly, impaired mental states, fever, V/D, diuretics}signal transduction pathway {Ans: transfer, amplify, distribute,modulated}ligand {Ans: extracellular chemical messenger that binds to interior of cell matched with target cell}germline mutation {Ans: happens in germ cells, inheritable, in all cells}Kidney buffering system {Ans: kicks in hours to days, not sufficient for acute imbalances, adjusts through secretion of H+ ions and bicarb conservation}Hypocalcemia causes {Ans: inadequate intake, impaired intestinal absorption, deposition of CA into bone or tissue, blood administration, decreased PTH or VIT D}