Advanced Pharmacology Nsg 533 Study Guide Rated A+

Who would be a candidate for prophylaxis of NSAID induced ulcer and what agents are appropriate? What if the patient is on cardio-protective (low dose) aspirin? What if an NSAID induced ulcer does develop. How should it be treated? {Ans: Candidate: -Candidates: Chronic Nsaid Use, Hx ulcers, Zollinger-Ellison Prevention Treatment- PPI, standard doses (most effective & best tolerated), Misoprostol (better than H2RA's, No Pregnancy)}Testosterone replacement (Low-T) {Ans: Testosterone replacement regimens should never be administered to men with normal serum testosterone levels, or in patients with isolated erectile dysfunction as the only sign of hypogonadism. Before initiating any testosterone replacement regimen in patients 40 years and older, patients should be screened for breast cancer, benign prostatic hyperplasia, and prostate cancer. All are testosterone-dependent conditions and theoretically could be worsened by exogenous administration of testosterone}Non-pharmacologic interventions for BPH {Ans: Lifestyle modification - limiting EToH, caffeine, avoid certain medications (Table 52-4)(e.g. decongestants, androgens, etc) as well as addressing co-morbidities (weight loss, etc) Watchful waiting is the most conservative approach for patients with mild symptoms or those with moderate symptoms without bother ◦Appropriate option for patients with mild symptoms (AUA-SI score ≤ 7), and for many with moderate to severe symptoms