Nurs 6630 Psychopharmacology Study Guide (20 Terms).

G Protein-Linked Receptors: Structure {Ans: These receptors all have the structure of seven transmembrane regions, meaning that they span the membrane seven times. Each of the transmembrane regions clusters around a central core that contains a binding site for a neurotransmitter.}The cytochrome P450 (CYP) enzyme system {Ans: mediates how the body metabolizes many drugs, including antipsychotics.}the soma {Ans: is the command center of the nerve and contains the nucleus of the cell}axosomatic {Ans: synaptic connections between the axon and the soma}agonist {Ans: produces a conformational change in the G-protein-linked receptor that turns on the synthesis of second messenger to the greatest extent possible}axon {Ans: Neurons send information via an ____ that forms presynaptic terminals as the ____ passes by (en passant) or as the ____ ends}axodendritic {Ans: synaptic connections between the axon and dendrites of two neurons}axoaxonic {Ans: synaptic connections between axons of the two neurons}The CYP enzyme {Ans: in the gut wall or liver converts the drug into a biotransformed product in the bloodstream. After passing through the gut wall and liver, the drug will exist partly as unchanged drug and partly as biotransformed drug.}full agonist {Ans: is generally