Exam Preparation: Nr-291 Pharmacology I Exam 2 Study Guide

1EXAM PREPARATION: NR-291 Pharmacology I Exam 2 Study Guide Effects of the Peripheral Vascular System Cholinergic - Parasympathetic Nervous System (feed and breed; rest and digest) oCholinergic effects (SLUD) Salivation, Lacrimation, Urination, Defecation oAnticholinergic effects (Mad as a Hatter) Hyperthermia, blindness, confused, dry mouth, urinary retention, shaking, grabbing invisible objects, tachycardia, absent bowel sounds, flushed skin, mydriasis Adrenergic - Sympathetic Nervous System (fight or flight) oAlpha effects Vasoconstriction (treat hypotension), CNS stimulation, relaxation of GI smooth muscles (decreased motility), constriction of bladder sphincter, contraction of pupillary muscles of the eye (dilated pupils), contraction of uterus, male ejaculation oBeta1 and Beta2 effects 1 - increased force of contraction (positive inotropic effect). Increased HR (positive chronotropic effect), increased conduction through AV node (positive dromotropic effect) 2 - bronchodilation (relaxation of the bronchi), glycogenolysis in the liver, increased renin secretion in the kidneys, relaxation of GI smooth muscles (decreased motility), uterine relaxation, inhibits histamine release from mast cells, increases intraocular pressure oDopaminergic effects Vasodilation (resulting in increased blood flow) to: renal (diuresis), mesenteric, coronary (increase CO and contractility without increasing HR), cerebral Chapter 36: Antihistamines, Decongestants, Antitussives, and Expectorants Know and apply pharmacology treatment for the common cold oCombination use of: antihistamines, nasal