Nurs 5315: Advanced Pathophysiology 2025 Uta Exam 3 Latest Updated 2025 2026 Verified & Complete

Guillain-Barre Syndrome {Ans: Life threatening *autoimmune* disease of Peripheral Nervous System leading to *ASCENDING PARALYSIS* (starts in extremities and moves up) *Dymyelination of axons in peripheral nervous system* *FOLLOWS VIRAL INFECTION* Treatment is supportive; ventilator support until recovery which can take weeks to years. Person may recover or die or it may become a chronic relapsing problem.}Unstable Angina {Ans: -Chest pain that is PROLONGED or RECURRENT at REST, or chest pain that is INCREASING in SEVERITY or FREQUENCY -Caused by a labile (unstable) thrombus that is does NOT occlude blood flow for any longer than 20 minutes -PERFUSION IS RESTORED BEFORE MYOCARDIAL NECROSIS OCCURS -Can progress to a heart attack}Anaphylactic Shock {Ans: Results from pathologic immune and inflammatory reaction to an antigen, leading to widespread VASODILATION. Type I hypersensitivity. IgE mediated.}Congenital Heart Disease {Ans: -Most common heart disease affecting children -Etiology is unknown in 90% of cases Causes: Genetic/environmental factors (multifactorial factors) Primary genetic factors (single gene disorders, chromosome disorders) Sole environmental factors (Accutane/isotretinoin for acne, alcohol, maternal rubella infection) Maternal Risk Factors: Age over 45, prior child with heart defect, poorly controlled diabetes during pregnancy, alcohol, congenital infection during pregnancy (rubella), aspirin, lupus, Dilantin/phenytoin/diphenylhydantoin for