NURS 5315 Advanced Pathophysiology UTA Exam 1 (Latest 2025 / 2026 Update) Real Questions and Verified Answers | 100% Correct | Already Graded A+. 1. What can Reactive Oxygen Species cause?: Heart disease, Alzheimers, Parkinsons, Amyotrophic Lateral Sclerosis (ALS), CV disease, HTN, HLD, DM, ischemic heart disease, HF, OSA. Lipid perioxidation, damage proteins, fragment DNA, less *protein synthesis*, chromatin destruction, damage mitochondria 2. What is the body's defense against ROS?: Antioxidants (Vitamin E, Vitamin C, cysteine, glutathione, albumin, ceruloplasmin, transferrin) 3. How are free radicals produced?: 1. Normal cellular respiration 2. Absorption of extreme energy sources (radiation, UV light) 3. Metabolism of exogenous chemicals, drugs, and pesticides 4. Transition of metals 5. Nitric oxide acting like a chemical mediator and a free radical 4. action potential: Process of conducting an impulse. Activates the neuron -- > the neuron depolarizes --> then repolarizes 5. Threshold potential: Point at which depolarization must reach in order to initiate an action potential 6. Hypokalemia and action potentials: HYPERpolarized (more negative, ex. - 100). Less excitable. Decreased neuromuscular excitability: weakness, smooth muscle atony, paresthesia, cardiac dysrhythmias 7. Hyperkalemia and action potentials: HYPOpolarized (more positive, ex: closer to 0). More excitable. Peaked T waves. When resting