Nr 565 Midterm Questions And Answers 100% Verified A+ Guaranteed

Explain what it means if a drug is an antagonist? {Ans: An antagonist according to our text is a drug that takes over a receptor without stimulating that receptor. We see the medication blocking the response of an agonist to that receptor. Such as seen in a beta-blocker keeping the adrenergic nerve activity from increasing the heart rate and therefore able to help decrease the heart rate of the patient taking the medication. Antagonists can make the agonist appear less potent. The effect of the antagonist depends on that of the affinity for the receptor and the blood levels noted in the patient (Woo RN PhD ARNP CPNP-PC CNL FAANP, Teri Moser et al., 2015).}What dosing of propranolol has been proven effective in reducing the incidence of migraine headaches? {Ans: Propranolol in doses of 20 to 80 mg 3 or 4 times daily has proved effective in reducing the incidence of migraine headache in some patients. The mechanism of action is related to prevention of beta receptor-induced vasodilation and promotion of increased extracellular levels of serotonin. For propranolol, if a satisfactory response to the maximum dose is not obtained in 4 to 6 weeks, the drug should be