Before giving drugs that alter glucose levels... {Ans: obtain and document: A thorough history, Vital signs, Blood glucose levels, HbA1c level, Potential complications and drug interactions, Assess the patient's ability to consume food. Assess for nausea or vomiting. Hypoglycemia may be a problem if antidiabetic drugs are given and the patient does not eat. If a patient is to take nothing by mouth (NPO) for a test or procedure, consult the primary care provider to clarify orders for antidiabetic drug therapy Keep in mind that overall concerns for any patient with diabetes increase when the patient:Is under stress, Is pregnant or lactating, Has an infection llness or trauma Thorough patient education is essential regarding: Disease process, Diet and exercise recommendations Self-administration of insulin or oral drugs, Potential complications}histamine 2 receptors {Ans: mediate acceleration of the heart rate and gastric acid secretion}Insulin glargine (Lantus) {Ans: Long-acting insulin. Onset: 2-4 hour. Peak: none. Duration 20 to 24 hours. Forms micro-precipitates that are slowly absorbed over 24 hours - provided constant level of insulin in body. Usually dosed once per day or every 12 hours. Sometimes referred to as basal insulin. NOT interchangeable with insulin detemir (Levemir)}Theophylline {Ans: xanthine