Nur 3145 Exam 1 Paper Questions And Answers (Verified Answers) Best For 2024 Exam

Pharmacokinetic Process: Drug Metabolism special considerations {Ans: Age, induction of drug-metabolizing enzymes, first-pass effect, nutritional status, competition between drugs}Interpatient variability in drug response (measurement) {Ans: The ED50 vs. LD50: effective/lethal dose for 50% of the population at that does. It is ideal to have a big difference between the ED and LD}Time course drug response: repeated dose {Ans: To achieve plateau drug levels- takes time to plateua}Time course drug response: single-dose {Ans: determined by metabolism and excretion}What are the types of drug categories? {Ans: 1. Prescription (well controlled, high risk); 2. OTC (self prescribed); herbals (can be dangerous-drug interaction)}Pharmacokinetic Process: Absorption and routes (3) {Ans: Movement of drug from outside of the body to the blood stream. 1. Percutaneous - skin/mucous membrane 2. enteral - GI tract 3. parenteral - injected into body}