What AA regulates protein synthesis?eIF2eIF5eIF2BWhat inhibits eIF2 activity? What does this lead to?eIF2 kinasesGCN2ATF4Integrated
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stress response (ISR)
Formation of eIF4 complex (Hint: 2 elements involved)
mTOR1/2
How can mTOR be activated?
How does mTOR lead to translational inhibition?
TSC1/2 complex cascade
TSC1/2 complex
mTOR inhibition by Sestrin
AMPK
How is AMPK activated?
AMPK alpha subunit
AMPK beta subunit
AMPK gamma subunit
What does AMPK activate?
What does AMPK inhibit?
3 AMPK upstream kinases
How does ATP
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