- Adverse Effects & Patient Teaching Intranasal Glucocorticoids ie: 1st gen Beclomethasone & budesonide 2nd gen: fluticasone propionate (Flonase) 1. most effective drugs for prevention and treatment of 2. prevent or suppress the major symptoms of allergic rhinitis: 3. most common Adverse Effects are 4. Serious Systemic effects are possible but are rare {Ans: 1. seasonal and perennial rhinitis 2. congestion, rhinorrhea, sneezing, nasal itching, and erythema 3. drying of the nasal mucosa and a burning or itching sensation. Sore throat, epistaxis, and headache 4. adrenal suppression and slowing of linear growth in children; Systemic effects are least likely with ciclesonide, fluticasone, and mometasone}MOA for Sulfonamides/Trimethoprim {Ans: Sulfonamides suppress bacterial growth by inhibiting key precursors of folate; Remember* all organisms depend on folate for DNA, RNA, and protein synthesis • Selective toxicity: it doesn't harm humans b/c mammalian cells can take up folate from their diet whereas bacteria must synthesize it from precursors}Patient-Centered Care Across the Life Span-Antifungal Agents Infants • Nystatin is used to treat oral candidiasis in Children/adolescents • Many antifungal agents are used safely in children, Pregnant women • Risks and benefits must be considered for administration during Breastfeeding women • (blank) are lacking regarding