Page 1 of 59 NURS 126 P:ARMACOLOGY =N NURS=NG PRACT=CE TEST BANK == F=NAL EXAM 2024-2025 UPDATED QUEST=ONS AND ACCURATE ANSWERS What are the uses of antitubercular drugs? Treatment of TB Prevention (chemoprophylaxis) -> Close contact to patients with recent TB infection -> =mmunosuppressed patients susceptible to infections What are the adverse effects of antitubercular drugs? ethambutol: optic neuritis (inflammation of the optic nerve) = altered color perception, changes in visual acuity, & vision loss isoniazid: peripheral neuropathy (i.e. burning, numbness, & tingling of extremities) rifampin: red-orange-brown discoloration of feces, saliva, skin, sputum, sweat, tears, tongue, & urine What is the contraindication of antitubercular drugs? Patients with major liver or renal dysfunctionPage 2 of 59 What are the drug interactions associated with antitubercular drugs? isoniazid phenytoin (antiepileptic) effects rifampin oral contraceptive effects What are nursing considerations for antitubercular drugs? Monitor kidney & liver function tests Administer isoniazid oral or =M =mplement direct observation therapy (DOT) prn -> Designated non-family member person to give medication and watch patient take it to ensure compliance Assess for therapeutic response -> in S/S (i.e. cough / fever) & weight gain -> Check C & S (culture & sensitivity = sputum) tests as well as