Immunology - Hmx Study Guide Rated A+

What antibody isotypes most efficiently neutralize protein function? (Select two answers.) {Ans: IgA and IgG}In humans, HCV follows a fairly standard course of infection. After initial exposure, the infection enters an acute phase. During the acute phase, there is a dynamic interplay between the virus and the immune system. Some individuals will mount an effective immune response and spontaneously clear the infection. Other individuals will not be able to clear HCV and the infection shifts into a chronic phase. Most of the damage (liver failure, cirrhosis) associated with HCV infection occurs in chronically infected individuals. There is significant interest in determining the genetic and immunological differences between individuals who spontaneously clear HCV infection and those who become chronically infected. There is enormous variation in the genes that encode MHC molecules (MHC class I and MHC class II). In humans, the genes that encode MHC molecules are known as the HLA (human leukocyte antigen) alleles. If you were to select any two individuals randomly off of the street, it is extremely unlikely that they would carry all of the same HLA alleles. This diversity at the MHC locus is the primary reason that it is so difficult to find an