Hmx Immunology Key-Concepts Review 2023 Exam Questions With All Correct Answers

MHC class I {Ans: endosomal pathway 1. enter cytoplasm 2. ubiquitination by protein 3. transported by TAP (transporter of antigen processing) into ER 4. binds to MHC 5. move to golgi 6. move to cell surface CD8+ T cell eradicate virus by apoptosis all cells with nucleus}(antibody isotope functions) IgG1 {Ans: complement fixation opsonization ADCC}epitope {Ans: An epitope is the part of the antigen that binds to a specific antigen receptor on the surface of a B cell. Binding between the receptor and epitope occurs only if their structures are complementary.}naive t cell activation {Ans: Occurs when the cell is stimulated with antigen and additional signals. Occurs primarily in secondary lymphoid organs (e.g. lymph nodes).}HSC {Ans: hematopoietic stem cell}e-selectin and e-selectin ligand {Ans: innate inflammation adhesion molecule low affinity interaction between neutrophil and lumen of endothelial cells slows the neutrophil down e-selection = endothelial surface e-selectin ligand = neutrophil}