Nr 546 Study Guide Rated A+

Starting doses for AD {Ans: Donepezil-5mg may increase to 10mg after 4-6 weeks Namenda-5mg, increase by 5mg each week, max 10mg BID Galantimine-IR-4mg BID after 4 weeks may increase to 8mg BID, after 4 more weeks may increase to 12mg BID; ER same titration schedule but dosed once daily, 8, 16, 24mg Rivastigimine-1.5mg BID, increase by 3mg every 2 weeks, titrate to tolerability max 6mg BID; transdermal 4.6/24hours, after 4 weeks increase to 9.5/24 hours max dose 13.3mg}Diagnosis of AD {Ans: AD is currently diagnosed through the exclusion of other causes of dementia, such as vascular disease, Lewy body dementia, Parkinson's disease, and Creutzfeldt-Jacob disease.}PRESCRIBING PEARLS {Ans: · Lurasidone (Latuda) should be taken with food, at least 350 calories, for maximum absorption. · Lithium carbonate (Lithobid) starting dose is reduced by at least 50% in clients with renal impairment. · Lithium levels can be increased by nonsteroidal anti-inflammatory drugs (NSAIDs) and angiotensin-converting enzyme (ACE) inhibitors and decreased by caffeine and mania.}Withdrawal {Ans: Physiological and psychological reactions that occur when the use of a substance is stopped abruptly}Aricept Precautions {Ans: · sick sinus syndrome · seizure disorder · Cholinesterase inhibitors are not recommended in pregnancy and