Nr 566 / Nr566 Final Exam Study Guide (Latest 2023/2024): Advanced Pharmacology For Care Of The Family - Chamberlain

Iron deficiency anemia monitoring: {Ans: - reticulocyte count 5 to 10 days after starting therapy, - Hgb, Hct, Ferritin at 4 weeks, then at 3 months and annually}pharmacokinetic implications of the physiologic changes in geriatrics {Ans: * Absorption - not dramatically different that younger adult *Distribution - increased fat stores, decreased total body water and serum albumin *Metabolism - decreased hepatic blood flow, decreased CYP 450 system function * Excretion - decreased renal mass and GFR and tubular secretion; serum creatinine is an unreliable marker or renal function}Anticoagulant preferred for high risk of CVA with Afib {Ans: -The 2012 ACCP guidelines recommend 150 mg of dabigatran twice daily as the anticoagulant therapy of choice rather than warfarin - For patients with persistent or paroxysmal AF at high risk for stroke, the recommendation is warfarin with a target INR between 2 and 3.}Folic acid deficiency drug therapy {Ans: - Oral folic acid 1 to 2 mg/day for 4 to 5 weeks - Hgb levels start to rise in a week -Initial dose: 1 mg/day in adults in children - Maintenance dose Infants 0.1 mg/day Pregnant or lactating women: 0.8 mg/day}Antiplatelet clinical use {Ans: *ASA - MI