Advanced Pharmacology Prescribers Study Guide Rated A+

Venlafaxine (Effexor) {Ans: Vanlafaxine (IR): starting dose 25mg/day and maximum dose 150mg/day typical, 375mg/day maximum Venlafaxine (ER): starting dose 37.5mg/day and maximum dose is 225mg/day EPISODIC MIGRAINE PREVENTION-OFF-LABEL USE: oral ER initial dose 37.5mg/day once daily for 3 days. then increase up to 75mg/day increments to a target dose of 75mg/day to 150mg/day once daily. NEUROPATHIC PAIN ASSOCIATED WITH DIABETES MELLITUS OFF LABEL USE: Oral ER initial dose 37.5mg/day then increase up to 75mg/day to a maximum dose of 225mg/day once daily.}NSAIDS duration of action: short acting (less than 6 hours)- Ibuprofen, diclofenac, ketoprofen and indomethacin. long acting (more than 6 hours) - Naproxen, celecoxib, meloxicam {Ans: patient counseling side effects of NSAIDS_ nausea, vomiting, gastritis, diarrhea, constipation, lack of appetite, rash, dizziness, headache, drowsiness. other important side effects are kidney failure (primarily with chronic use), liver failure, ulcers, prolonged bleeding, fluid retention, gastric/intestinal bleeding, ulcers, and perforation.}common and serious side effects of cymbalta and effexor {Ans: headache,drowsiness, fatigue, insomnia, dizziness, tremor, abdominal pain, nausea, Xerostomia, constipation, diarrrhea, weight loss, weakness, diaphoresis, libido changes, erectile dysfunction. Serious side effects: Suicidality, Serotonin syndrome, hepatotoxicity, mania, syncope, SIADH, hyponatremia, acute angle glucoma.}CDC recommendations for management of acute pain