Bmb 402 Exam 3 Latest Questions And Answers

Acetyl-CoA Carboxylase {Ans: Produces Malonyl-CoA from Acetyl-CoA in the first committed step of fatty acid biosynthesis (makes a 3C from a 2C) Subject to allosteric and hormonal control EX: citrate stimulates ACC, Long-chain fatty acyl-CoAs are feedback inhibitors of the enzyme, and further control of activity is accomplished through covalent modification}Chylomicrons in Peripheral Tissue Capillaries {Ans: Chylomicrons bind to binding sites on the endothelium of the capillaries in skeletal muscle and adipose tissue thanks to their polar surface of apolipoproteins}LDL {Ans: The second highest density lipoprotein (second lowest fat content) Contains a tremendous amount of cholesterol in the form of Cholesteryl Esters (CEs) after the TAG from VLDL has been removed Animal cells acquire cholesterol either by synthesizing it or by taking up LDL}Lipid Metabolism Regulation PKA {Ans: PKA activates TAG lipase activity to increase energy supply PKA signals for glycogenolysis and breakdown of glucose for energy}Carnitine {Ans: Carries acyl groups across the mitochondrial membrane Free Fatty Acid activation occurs in the cytosol, but they are oxidized in the mitochondrion A long-chain fatty acyl-CoA CANNOT directly cross the inner mitochondrial membrane This molecule is used in a transesterification reaction by carnitine palmitoyl transferases I and