Pharmacology Final Exam Questions With Answer

Consider these patient variables when prescribing meds: {Ans: pathophysiology (ie: renal excretion of aminoglycosides in treating bacterial infections or organ disease), genetics, age, gender (higher percentage of body fat and estrogen may affect pharmacodynamic response in women), ethnicity (AAs poor response to ACEs), diet (MAOs + tyramines =>HTN crisis), weight, protein status, allergies, drug-drug interactions, side effects}life-long thyroid hormone replacement {Ans: Levothyroxine / Synthroid (T4)}4 routes not subjected to 1st pass by liver: {Ans: IV, IO, sublingual, inhalation}prostatitis with STI treated with {Ans: Rocephin or Cefixime + Doxycycline}treatment of gonorrhea (shot & z-pack): {Ans: Ceftriaxone IM x 1 AND Azythromycin PO x 1 dose}Drugs Used for Migraine Headache Prophylaxis {Ans: •Beta-blockers •Tricyclic antidepressants •Anticonvulsants •Calcium channel blockers (B2 & CoQ-10)}Podofilox 0.5% solution/gel for 3 days Imiquimod 5% cream 3x/week up to 16 weeks Podophyllin Resin 10%-25% in tincture of benzoin weekly PRN Trichloroacetic Acid or Bichloracetic Acid weekly PRN {Ans: Treatment of HPV (genital warts) HPV vaccine now recommended until age 26.}Heparin is a naturally occurring anticoagulant released by mast cells. Unfractionated Heparin: {Ans: Activates antithrombin III, blocks intrinsic clotting pathway; aPTT 3x normal is therapeutic. Indicated for: DVT, PE, MI/ACS, acute