Final Exam: Nr 565 / Nr565 Advanced Pharmacology Exam Review | Weeks 5-8 Covered| Complete Guide With Questions And Verified Answers (2023/ 2024)

Characteristics of Complicated UTI {Ans: symptoms > 7 days Rigors flank pain DM, pregnancy, immunocompromised, renal calculi recent d/c from hospital for nursing home 3 or > UTI in past year failed antibiotics within past 4 months resident at ECF}Antihistamines antiemetics {Ans: anticholinergic, histamine-blocking; Dramamine, Benadryl, Vistaril, Antivert}Antiviral Neuraminidase inhibitor mechanism of action {Ans: cleaving viral attachment to the host cell surface allow for viral circulation}famciclovir indications {Ans: HSV-1 & 2, EBV, Hep B}PPI drug interactions {Ans: CYP 450 enzymes, decreased effects of certain antivirals, decreases absorption of ketoconazole, ampicillin, digoxin, and iron salts, monitor INR with coumadin and PPIs}Scopalamine (Transderm Scop) precuations/contraindications {Ans: caution: open-angle glaucoma, eldery-increases CNS effects, GI or bladder neck obstruction contraindicated: narrow-angle glaucoma}P/neurokinin 1 receptor antagonist antiemetic {Ans: Aprepitant (emend)}Ivermectin (Stromectol) indications {Ans: tissue nematodes}what causes most diarrhea? {Ans: infection, food or drug ingestions, or inflammatory bowel disease}tinidazole (Tindamax): MOA {Ans: deactivates DNA and other proteins}Proton Pump Inhibitors (PPIs) indications {Ans: hyperacidity, duodenal & gastric ulcers, erosive gastritis, Zollinger-Ellison syndrome, part of regimen for PUD, GERD}Amphotericin B {Ans: severe systemic fungal infections: HIGHLY TOXIC}Acyclovir (Zovirax) indications {Ans: HSV-1 & 2, varicella-zoster virus,