Nurs 5334 Exam 3 Questions And Complete Correct Answers

Allergic conjunctivitis {Ans: o Mast-cell stabilizers o NSAIDS (ketorolac) Side effects with long term use? Cataract, eye infection and elevation of interocular pressure o Ocular decongestants (naphazoline, phenylephrine) Activating alpha one adrenergic receptor on the blood vessels, causing vasoconstriction}How does metformin work? {Ans: o Inhibits glucose production in the livero Reduces glucose absorption in the guto Sensitizes insulin receptors in target tissues (fat and skeletal muscle) thus increase glucose uptake and response to whatever insulin is available}How does alcohol effect? {Ans: Inhibits the breakdown of lactic acid}Drug Interactions? {Ans: Exercise caution with other medications that lower blood pressure o Organic nitrates, antihypertensive drugs, PDE-5 inhibitors used for ED o Inhibitors of CYP3A4 Cataract surgery: "Floppy-iris syndrome"}o What are the adverse effects of cimetidine? {Ans: Antiandrogenic effects CNS effects Pneumonia IV bolus: Can cause hypotension and dysrhythmias}o Alpha1-adrenergic antagonists (dynamic obstruction) {Ans: Terazosin [Hytrin] Doxazosin [Cardura] Tamsulosin [Flomax] Alfuzosin [Uroxatral] Silodosin [Rapaflo] MOA Blockade of alpha1 receptors relaxes smooth muscle in the bladder neck (trigone and sphincter)}o Sucralfate: MOA? Uses? {Ans: Creates protective barrier for up to 6 hours Acute ulcers and maintenance therapy}insulin drug interactions {Ans: o Hypoglycemicagents Can intensify the