Chem 1005 Final Exam Review Questions With Complete Solutions

The process of ketogenesis refers to the conversion of acetyl-CoA to which of the following compounds? {Ans: D-3-hydroxybutyrate or β-hydroxybutyrate}In the reaction catalyzed by cholesteryl ester transfer protein (CETP), the VLDL particle receives which of the following compounds from HDL particles? {Ans: Cholesteryl-ester; HDL particles interact with VLDL particles to exchange cholesteryl ester for triacyclglycerols}Under conditions when glucose oxidation is elevated, the acetyl-CoA produced will allosterically activate which of the following enzymes leading to an increase in the production of oxaloacetate? {Ans: Pyruvate carboxylase; Pyruvate carboxylase will synthesize oxaloacetate in the mitochondria which will assist in the synthesis of citrate. Citrate can be shuttled out of the mitochondria to be used for cytosolic fatty acid synthesis.}In liver, which of the following key inhibitory events ensures that newly synthesized palmitoyl-CoA is not immediately oxidized? {Ans: Inhibition of carnitine-palmitoyl transferase-I (CPT-I) by malonyl-CoA}Which of the following statements is consistent with nitrogen transport in the fasted state? {Ans: The urea cycle will be active; In the fasted state the urea cycle will be active, all other processes are not consistent with the fasted state metabolism. Glutaminase will be active; hepatic glutamate dehydrogenase will be freeing ammonia from glutamate