Nurs 534 Advanced Physiology 46 Correctly Answered Questions Latest Update

• Collagen is an important protein of the ECM; collagen is synthesized by fibroblasts. • Cell adhesion molecules (CAMs): integrins, cadherins, and selectins • Elastin: an elastic protein in connective tissue that allows tissues to maintain shape during contractions/ stretching. • Fibronectin: a glycoprotein that binds to receptors on the membrane (integrins) and to collagen; important in cell adhesion and growth differentiation. Slide #6 {Ans: Components of the extracellular matrix (ECM)}Passive or diffusional transport is sub-categorized into simple diffusion and facilitated transport. Distinguish between these two forms of transport. {Ans: Simple diffusion: passive transport Example: osmosis Facilitated diffusion: requires transport protein (needs to hitch a ride) Does not require ATP/energy Examples: glucose requires insulin to enter or leave cells}• Exerts a "fluidizing" effect on the membrane. • Serves as a molecular "organizing" force. • A precursor for cell signaling cascades (e.g., phosphatidy [4,5] biphosphate, PIP2). slide 15 {Ans: Cholesterol is an important structural component of the membrane}. Why is it important for glucose to be transported via a secondary transport process and using a carrier-mediated protein into and out of a small intestinal epithelial cell? {Ans: Na+ is the "gas" for SGLT2 GLUT2 is a "free