Exam Review With Complete Solutions 2024

CSF analysis- TB mening {Ans: Pressure variable. Glucose low to megalow. WBCs vary, mostly lymphocytes. Protein elevated. AFB stain +}TB risk assessment {Ans: Depends on prevalence of TB patients in facility (# pt/year) and community and on any TST conversions among HCP. CDC algorithm turns into low, medium, or potential ongoing transmission risk categories for individual hospital areas. Has implications for the need to serially test HCP.}PPV {Ans: Likelihood that a + test represents a true case (% T+/all+); depends on the test and on prevalence of disease in population}Hepatitis A epidemiology {Ans: Incidence has tanked since VACCINE introduced. Fecal oral spread; poor hygiene and intimate contact are risk factors. Kids usually asymptomatic. Contagious before symptoms start. No chronic carriage. incubates15-50 days.}Toxin production tests {Ans: Many ways of doing, including EIA and HPLC. limulus amebocyte lysate tests for endotoxin.}Concentration vs time dependent antibiotic dosing {Ans: CD means you want to spike the initial concentration really high, and if it dips below MIC before next dose it's ok because of "post-antibiotic effect" still killing. aminoglycosides, fluoroquinolones are [dependent]. Time dependent means you don't need a high [], just to keep the [] above the MIC