NSC 330 Antifungals Questions And Answers A+ Graded 2024 1 / 3 1. What are fungi? Larger, more complex than bacteria Infection often caused by inhalation from contaminated soil Molds, yeasts, dermatophytes 2. What are ex- amples of drug classes of anti- fungals? 3. What are ex- amples of poly- enes? 4. How is ampho- tericin B adminis- tered? 5. What is the black box warning for amphotericin B? 6. What are AEs of amphotericin B? 7. What are nurs- ing implications of amphotericin B? 8. How are nys- tatins adminis- tered? Polyenes Azoles Echinocandins Pyramidine analogs Amphotericin B Nystatin IV only Given 4-12 weeks Serious systemic infections only Multisystem organ failure (liver, renal) Respiratory failure Cardiac arrest GI bleed Renal failure leukopenia Thrombocytopenia Monitor renal labs pre/post Monitor hepatic enzymes Monitor for adverse effects/pre-medicate - antiemetics, antihistamines, aspirin Follow hydration protocol (500 ml boluses before/after) Oral or topical/vaginal 9. No serious adverse effectsNSC 330 Antifungals Questions And Answers A+ Graded 2024 2 / 3 What are AEs of nystatin? 10. What are uses of nystatin? 11. What are exam- ples of azoles? 12. What is known about itracona- zole? 13. What are AEs of azoles? 14. What are nurs-