2021 ATI PN PHARMACOLOGY EXAM REVIEW QUESTIONS AND ANSWERS WITH RATIONALES GRADED A+ 1. A 52-yr-old male patient has received a bolus dose and an infusion of alteplase (Activase) for an ST-segment elevation myocardial infarction (STEMI). Which patient assessment would determine the effectiveness of the medication? A Presence of chest pain B Blood in the urine or stool C Tachycardia with hypotension D Decreased level of consciousness Correct ans - A Alteplase is a fibrinolytic agent that is administered to patients who have had an STEMI. If the medication is effective, the patient's chest pain will resolve because the medication dissolves the thrombus in the coronary artery and results in reperfusion of the myocardium. Bleeding is a major complication of fibrinolytic therapy. Signs of major bleeding include decreased level of consciousness, blood in the urine or stool, and increased heart rate with decreased blood pressure.2. A 74-yr-old man with a history of prostate cancer and hypertension is admitted to the emergency department with substernal chest pain. Which action will the nurse complete before administering sublingual nitroglycerin? A Administer morphine sulfate IV. B Auscultate heart and lung sounds. C Obtain a 12-lead electrocardiogram (ECG). D Assess for coronary artery disease risk