Pharm 152 Pharmacology Mcqs Pharmacol Therapeutics

PRACTICE Qs PRINCIPLES OF DR UG ACTION SMBM1. Receptors are macromolecules that a. Are designed to attract drugs b. Are resistant to antagonists c. Exist as targets for physiological neurotransmitters and hormones d. Are only on the outer surface of cellse. Are only inside of cells 2. All of the following are capable of initiating a signal transduction process EXCEPT a. Combination of an agonist with its receptor b. Combination of an antagonist with its receptor c. Combination of a neurotransmitter with its receptord. Combination of a hormone with its receptor3. Which of the following chemical bonds would create an irreversible combination of an antagonist with its receptor? a. Ionic bond b. Hydrogen bond c. Van der Waals bond d. Covalent bond 4. Potency is determined by a. Affinity alone b. Efficacy alone c. Affinity and efficacy d. Affinity and intrinsic activity e. Efficacy and intrinsic activity5. Which of the following best describes what the term tachyphylaxis means? a. An increase in the rate of the response, for example, an increase of the rate of muscle contractionb. Immediate hypersensitivity reactions (i.e., anaphylaxis) c. Prompt conformational changes of the receptor such that agonists, but not antagonists, are able to bind and