Nr565 Week 4 Midterm Exam Review 2025 | Advanced Pharmacology Foundations | Comprehensive Study Guide For A+ Mastery

NR565 WEEK 4 MIDTERM EXAM REVIEW 2025 | ADVANCED PHARMACOLOGY FOUNDATIONS | COMPREHENSIVE STUDY GUIDE FOR A+ MASTERYWhat is the prototype drug for NSAIDs? - ---CORRECT ANSWER--,--Ibuprofen (Motrin) What category do NSAIDs belong to? - ---CORRECT ANSWER--,--Cyclooxygenase Inhibitors, Propionic Acid Derivative (Nonsteroidal Anti-inflammatory Drugs) What are the primary functions of NSAIDs? - ---CORRECT ANSWER--,--To treat fever, inflammation, and pain. What distinguishes first-generation NSAIDs from second-generation NSAIDs? - ---CORRECT ANSWER--,--First-generation NSAIDs are covered here, while second-generation NSAIDs will be covered later. How do NSAIDs inhibit cyclooxygenase (COX) enzymes? - ---CORRECT ANSWER--,--NSAIDs temporarily inhibit COX-1 and COX-2, causing reversible inhibition. What are the therapeutic uses of NSAIDs? - ---CORRECT ANSWER--,--NSAIDs are used for pain relief, reducing fever, and decreasing inflammation. What is the major complication associated with NSAID use? - ---CORRECT ANSWER--,--Hemorrhage, particularly in the gastrointestinal system.What side effect can occur due to renal impairment from NSAIDs? - ---CORRECT ANSWER--,--The kidneys may lack the necessary prostaglandins for normal function. What serious condition can a rash from NSAIDs indicate? - ---CORRECT ANSWER--,--Stevens-Johnson Syndrome (SJS). What is a black box warning associated with first-generation NSAIDs? - ---CORRECT ANSWER--,--Increased risk of GI bleeding and thrombotic events (e.g., MI and stroke). What should clients be cautious