Nagelhout Pharmacology Exam 1 Review Questions With Answers

A basic drug in a solution at it's pKa {Ans: is 50/50 ionized/non-ionized}Efficacy (intrinsic activity) {Ans: the ability of a drug to produce the desire response}What is the distribution half-life? {Ans: The Alpha half-life}What is the volume of distribution (Vd)? {Ans: Explains where the drug is distributed in the body. If a drug is >0.6L/kg -Drug is widely distributed -Likely lipid soluble If a drug is <0.4L/kg -Drug is largely contained in plasma -Likely water soluble.}Plane in which there is delayed thoracic respiratory efforts; dilated pupils, no corneal reflex, sluggish pupillary reflex to light {Ans: Stage III plane iii}Define: sympatholytic {Ans: Blocks adrenergic neurotransmitters (beta blockers)}