MSN 571 PHARM FINAL EXAM EXAM 2024-2025 QUESTIONS and ANSWERS WITH RATIONALE A patient was diagnosed as having health care-associated methicillin-resistant Staphylococcus aureus (HCA-MRSA). Which medication is most likely to be ordered for treatment? A. Amo B. Clindamycin C. Tetracycline D. Vancomycin - ANSWER-D Vancomycin is effective in treating HCA-MRSA. MRSA is resistant to all penicillins and cephalosporins. The bacteria are resistant to tetracycline and clindamycin as well Which action should the nurse take before administering intravenous (IV) penicillin? A. Assess the patient for allergies B. Flush the IV site with normal saline C. Review the patient's intake and output record D. Determine the latest creatinine clearance results - ANSWER-A The principle adverse effect of penicillins is allergic reaction. Penicillins are contraindicated in pts with a history of severe allergic reactions to penicillins, cephalosporins, or carbapenems. IV patency is important, as is monitoring renal function, because impairment can cause penicillins to reach toxic levels; however these are not as important as determining allergy status The nurse is monitoring a patient on vancomycin for indications of major toxicity. Which test should be monitored closely? A. Creatinine level B. Alkaline phosphatase C. Electroencephalogram D. Creatine phosphokinase (CPK) - ANSWER-A The creatinine level