EXAM 1: Surgical Wounds EXAM 2025 QUESTIONS AND CORRECT ANSWER What can assist in offsetting the effect of steroids in terms of wound healing? (3) -vitamin A -can reverse inhibitory/anti-inflammatory effect of steroids -stimulates epidermal turnover, restores structure Acute wound results from loss of anatomic tissue structure due to transfer of -kinetic -chemical -thermal energy (cut, blow, burn, pressure, other impact) When a wound occurs there is a breakdown in skin due to: loss of continuity of epithelium Most surgical wounds are ACUTE, and wound healing is normally completed in: 6-12 weeks (some tissues heal more quickly than others) Wound healing will eventually result in: wound closure 4 phases of wound healing & timing -1. hemostasis/coagulation (seconds to hours) -2. inflammation (hours to days) -3. proliferation (days to weeks) -4. maturation via contraction and remodeling (weeks to months/years)What leads to formation of a chronic nonhealing wound? if wound healing cascade is arrested in ANY of the 4 phases 1. Hemostasis and coagulation phase: begins when? (3) -right after injury/wound occurred -immediate vasoconstriction to prevent further blood loss -formation of blood clot to seal vessel 1. Hemostasis and coagulation phase: what gets activated? (4) -coagulation and complement cascades -plts create a