NURS 4010 EXAM 2 MEDICATIONS ACTUAL EXAM UPDATED QUESTIONS AND ACCURATE SOLUTIONS VERIFIED 100% COMPLETE DOCUMENT FOR STUDY SSRI selective serotonin reuptake inhibitor MOA of SSRI blocks the reuptake of 5HT (serotonin) and therefore increases the availability of serotonin at the synapse Fluoxetine, Sertaline, Fluvoxamine, Parotxetine, Citalopram, Escitalopram, Vilazodone, Vortoxetine examples of SSRIs Fluoxetine PROZAC. Low dose DAILY. (first SSRI of its kind) Sertraline Zoloft. can cause stomach issues. take with food to increase absorption and decrease S/SX Fluvoxamine Luvox. Treats OCD/social anxiety disorders. Paroxetine most sedating and most weight gain related to this SSRI. Citalopram/Escitalopram SSRIs that can prolong the QT intervalVortioxetine (Trintellix) SSRI is safe in the elderly and off label used to treat geriatric depression SE of SSRIs sweating, yawning, decreased sex drive, palpitations, diarrhea, N/V, loss of appetite SNRIs serotonin and norepinephrine reuptake inhibitors MOA of SNRIs inhibit serotonin and NE reuptake SE of SNRIs N/V, urinary retention, increased BP, increased pulse, sexual dysfunction + SSRI SEs Venlafaxine SNRI - Effexor. Used to treat depression, GAD, OCD * lower doses of this = more SER and less NE* *higher doses of this = more NE and less SER* Desvenlafaxine SNRI- extended release anti-depressant. metabolized by the