Nsg-318 Exam 1 Questions With Answer

what is the importance of pharmacogenetics {Ans: -shows how different ethnicities react to drugs -used for individualized drug regimens -shows what different ethnicities can become easily toxic to (Asians with narcotics; Europeans with cardiac meds)}placebo effect {Ans: drug response not attributed to chemical drug properties}free drugs {Ans: can exit blood vessels and reach their site of action causing pharmacological response (too high of free drug accumulation can cause side effects, adverse effects, or toxicity)}basic drugs bind to {Ans: alpha 1 acid glycoprotein (AGPs)}Orphan Drug Act of 1983 {Ans: (used in tx of rare diseases) -fed funding of grants/contracts to perform trials with these meds -50% tax credit for costs of clinical testing -exclusive rights to market drug for 7 years from marketing approval date}gtts are rounded to the {Ans: nearest whole number}