Pharm Exam Graded A Latest Version Questins And Answers

MAO-B inhibitor - Selegiline (Eldepryl, Zelapor) {Ans: Inhibits the dopamine metabolizer Used w/ levodopa to prolong it staying in the body, improves motor function Stops working for the most part after 12-24 mo. Give last dose by 12 noon Adverse effects: Mainly insomnia, drug interactions w meperidine or SSRIs}Phenytoin (Dilantin) is for {Ans: Gold standard drug for tonic-clonic or partial seizures and some CV problems Binds to albumin Adverse effects: Nystagmus Ataxia Sedation Gingival hyperplasia Effects on pregnancy and CV system Diplopia (double vision) Cognitive impairment Many drug interactions}What do you give for pancreatitis pain? {Ans: Demoral not morphine b/c spasm of Odi can cause biliary colic Don't give morphine to head injury patients}Most widely prescribed drug in the US that can be combined with aspirin, tylenol, ibuprofen {Ans: Hydrocodone}Glutamate (NMDA) {Ans: Prolonged increase can kill neurons and cause Alzheimer's decreased NMDA can cause psychosis}Ergot alkaloids (Ergotamine) is for {Ans: Agonist of serotonin receptors to help w. migraines (second line drug for migraine)}