Pharmacokineticsblood /plasmaDistributionMetabolismEliminationI.V. because your putting entire dose into a patients vein and bypassing absorptionI.V.
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Route
Rectal administration
4-5 half-lives of a drug
Half life of a drug
half life of a drug
half life of a drug
first-order (linear) pharmacokinetics
Zero-order (nonlinear) pharmacokinetics
CYP3A4 substrate drugs
laboratory research to develop the new drug, Preclinical research with animal testing for safety, Clinical research on healthy human subjects to assess medication
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