Which of the following findings should alert a health care professional that a patient is developing a potentially serious adverse reaction to interferon beta-1b (Betaseron)? 1. Blue-green skin discoloration 2. Twitching eyelids 3. Tinnitus 4. Fatigue {Ans: Answer 4. Rationale: ​Because of the potential for bone marrow suppression and decreased platelet count, patients should report unexplained bruising, bleeding, or fatigue. Interferon beta-1b can cause skin, sclerae, and urine to turn a blue-green color.}Prior to discharge, the nurse plans for patient teaching related to side effects of phenothiazines to the patient, family, or caregiver. Which of the following should be included? 1. The patient may experience withdrawal and slowed activity. 2. Severe muscle spasms may occur early in the therapy. 3. Tardive dyskinesia is likely early in therapy. 4. Medications should be taken as prescribed to prevent adverse effects. {Ans: Answer 2. Rationale: Acute dystopias, or severe muscle spasms, particularly of the back, neck, face, or tongue, may occur within hours or days of the first dose of a phenothiazine drug and should be reported immediately. Options 1, 3, and 4 are incorrect. Social withdrawal may be a symptom of the disease but is not related to the medication.