SIADH {Ans: Caused by excessive secretion of ADH leading to excessive water reabsorption. Caused by CNS infections (meningitis), brain tumors, brain trauma, children with pulmonary disorders (pneumonia, asthma, cystic fibrosis), and children receiving positive pressure ventilation. HIGH and DRY}Type 1 DM {Ans: Autoimmune destruction of insulin-producing pancreatic beta cells in individuals who are genetically predisposed}Central (neurogenic) DI {Ans: Inadequate production of vasopressin (ADH) Caused by brain tumors, brain trauma, CNS infection, and neurosurgery}Spina Bifida Types {Ans: Spina bifada occulta- the incomplete closure of vertebrae usually in the lumbosacral area without protrusion of the spinal cord or meninges Spina bifida cystica- a visible defect with an external saclike protrusion Meningocele- sac encases CSF and meninges (no neural elements) Myelomeningocele- sac encases CSF, meninges, and nerves}JIA s/s {Ans: Fever Rash lymphadenopathy Splenomegaly Hepatomegaly Slow or uneven growth of extremities may occur Pain, stiffness, loss of motion, and swelling occur in large joints}Muscular Dystrophy Tx {Ans: NO effective tx Prednisone may be used to increase muscle bulk Symptomatic tx PT/OT to increase mobility ROM Prevent obesity Genetic counseling Pt treated at home, goes to hospital for respiratory management}